K2-B4-3e

MedChem Express

K2-B4-3e

14

Research Use Only

C53H64ClN9O7S

1006.65

K2-B4-3e is a potent BRD4 PROTAC. K2-B4-3e induces BRD4 degradation with a DC50 value of 66 nM[1].

CCC(C1=CC2=C(N(C1=O)C3=CN(C(C=C3)=O)CC(OC)=O)CN(CC2)C(OCCC4CCN(CC4)CC5CCN(CC5)C(C[C@@H]6N=C(C7=C(N8C(C)=NN=C68)SC(C)=C7C)C9=CC=C(C=C9)Cl)=O)=O)C

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