K41498 (TFA)

MedChem Express

K41498 (TFA)

10

99.40

K41498 TFA is a potent and highly selective CRF2 receptor antagonist with K i values of 0.66 nM, 0.62 nM and 425 nM for human CRF 2alpha , CRF 2beta and CRF 1 receptors respectively. K41498 TFA is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF 2alpha - and hCRF 2beta -expressing cells. K41498 TFA can be used for hypotension study [1] .

-20°C,-80°C

12352202