K783-0308 [422554-29-8]
HY-115906
CAS Number422554-29-8
Product group Chemicals
Molecular Weight333.43
Overview
- SupplierMedChem Express
- Product NameK783-0308 [422554-29-8]
- Delivery Days Customer10
- CAS Number422554-29-8
- CertificationResearch Use Only
- Molecular FormulaC21H23N3O
- Molecular Weight333.43
- Scientific DescriptionK783-0308 is a potent and selective dual inhibitor of FLT3 and MNK2 with IC50 values of 680 and 406 nM, respectively. K783-0308 inhibits the growth of MOLM-13 (IC50=10.5 microM) and MV-4-11 (IC50=10.4 microM) cells. K783-0308 promotes acute myeloid leukemia (AML) cell apoptosis and cell cycle arrests in the G0/G1 phase[1].
- SMILESO=C(C1=CC=C2C(N=CN2C3=CC=C(CC)C=C3)=C1)NC4CCCC4
- UNSPSC12352200