K882

MedChem Express

K882

5

Research Use Only

C18H16N2O2

292.33

K882 (Compound 4e) is a Src inhibitor, with KD of 0.315 microM. K882 induces Apoptosis. K882 inhibits XIAP and Survivin. K882 inhibits the activation of PI3K/Akt/mTOR, Jak1/Stat3, Ras/MAPK signaling pathways. K882 shows anti-tumor activity against non-small cell lung cancer[1].

COC1=CC(/C=C/C2=NC=NC3=CC=CC=C23)=C(OC)C=C1

12352200