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KAN0438757 [1451255-59-6]

KAN0438757 [1451255-59-6]

T11741
TargetMol Chemicals
CAS Number1451255-59-6
Product group Chemicals
Estimated Purity99.80%
Molecular Weight447.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    KAN0438757 [1451255-59-6]
  • Delivery Days Customer
    4
  • CAS Number
    1451255-59-6
  • Certification
    Research Use Only
  • Chemical Name
    KAN0438757
  • Estimated Purity
    99.80%
  • Molecular Formula
    C21H18FNO7S
  • Molecular Weight
    447.43
  • Scientific Description
    KAN0438757 is a selective and potent inhibitor of the metabolic kinase [PFKFB3] with an IC50 of 0.19 microM.
  • Shelf life instruction
    3 years
  • SMILES
    OCCOC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)cc1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Gustafsson NMS, Färnegårdh K, Bonagas N, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018,9(1):3872. doi: 10.1038/s41467-018-06287-x
    Read this paper

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