KAP3 antibody

GeneTex

KAP3 antibody

9

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

KIFAP3

kinesin associated protein 3

dJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; smg GDS-associated protein; Smg-GDS

Rabbit

IgG

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 Armadillo repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203