(+)-Kavain [500-64-1]

MedChem Express

(+)-Kavain [500-64-1]

10

500-64-1

Research Use Only

99.98

C14H14O3

230.263

(+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the alpha4beta2delta GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4].

O=C1C=C(OC)C[C@H](/C=C/C2=CC=CC=C2)O1

2°C to 8°C

12352200