KB-0742 (dihydrochloride)

MedChem Express

KB-0742 (dihydrochloride) [2416874-75-2]

10

2416874-75-2

Research Use Only

99.24

C16H27Cl2N5

360.33

KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1 . KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity [1] .

N[C@@H]1C[C@@H](NC2=CC(C(CC)CC)=NC3=CC=NN23)CC1.[H]Cl.[H]Cl

2°C to 8°C

12352200