Bio-Connect

KB03-SLF

HY-147196
MedChem Express
Molecular Weight1018.51
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KB03-SLF [2384184-42-1]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C50H63ClF3N5O12
  • Molecular Weight
    1018.51
  • Scientific Description
    KB03-SLF (compound 6) is an electrophilic PROTAC degrader that binds to DCAF16 to degrade the nuclear protein FKBP12. KB03-SLF can be used in cancer research[1]. (Pink: Ligand for target protein SLF (HY-114872); Black: Linker (HY-W040168); Blue: Ligand for E3 ligase (HY-169968)).
  • SMILES
    O=C([C@H]1N(CCCC1)C(C(C(C)(C)CC)=O)=O)O[C@@H](C2=CC(NC(CCOCCOCCNC(CCNC(C3=CC(NC(CCl)=O)=CC(C(F)(F)F)=C3)=O)=O)=O)=CC=C2)CCC4=CC(OC)=C(C=C4)OC
  • UNSPSC
    12131703