KB03-SLF
HY-147196
Overview
- SupplierMedChem Express
- Product NameKB03-SLF [2384184-42-1]
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC50H63ClF3N5O12
- Molecular Weight1018.51
- Scientific DescriptionKB03-SLF (compound 6) is an electrophilic PROTAC degrader that binds to DCAF16 to degrade the nuclear protein FKBP12. KB03-SLF can be used in cancer research[1]. (Pink: Ligand for target protein SLF (HY-114872); Black: Linker (HY-W040168); Blue: Ligand for E3 ligase (HY-169968)).
- SMILESO=C([C@H]1N(CCCC1)C(C(C(C)(C)CC)=O)=O)O[C@@H](C2=CC(NC(CCOCCOCCNC(CCNC(C3=CC(NC(CCl)=O)=CC(C(F)(F)F)=C3)=O)=O)=O)=CC=C2)CCC4=CC(OC)=C(C=C4)OC
- UNSPSC12131703