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KCC2 antibody

GTX133130
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSlc12a5
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Overview

  • Supplier
    GeneTex
  • Product Name
    KCC2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.92 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57138
  • Target name
    Slc12a5
  • Target description
    solute carrier family 12, member 5
  • Target synonyms
    electroneutral potassium-chloride cotransporter 2; KCC2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; K-Cl cotransporter 2; mKCC2; mKIAA1176; neuronal K-Cl cotransporter; solute carrier family 12 member 5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ91V14
  • Protein Name
    Solute carrier family 12 member 5
  • Scientific Description
    Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Combination of repetitive transcranial magnetic stimulation and treadmill training reduces hyperreflexia by rebalancing motoneuron excitability in rats after spinal cord contusion. Wang S et al., 2022 Apr 1, Neurosci Lett
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