KCNIP3 Polyclonal Antibody

Reddot Biotech

KCNIP3 Polyclonal Antibody

5

1.62 mg/ml

KCNIP3

potassium voltage-gated channel interacting protein 3

A-type potassium channel modulatory protein 3; calsenilin; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; DREAM; DRE-antagonist modulator; KCHIP3; Kv channel interacting protein 3, calsenilin; kv channel-interacting protein 3; potassium channel interacting protein 3

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

-20°C

12352203