KDELR2, Mouse (Cell-Free, His)

MedChem Express

KDELR2, Mouse (Cell-Free, His)

14

Research Use Only

90.0

Kdelr2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

1110007A14Rik, ER lumen protein-retaining receptor 2, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2

ER lumen protein-retaining receptor 2

KDELR2 Protein, a membrane receptor, crucially maintains endoplasmic reticulum (ER) resident proteins localization. It binds the K-D-E-L sequence motif, retaining these proteins within the ER. This interaction facilitates vesicle-mediated recycling, ensuring proper subcellular localization through Golgi-to-ER protein return. KDELR2s pH-dependent binding, optimal at pH 5-5.4, underscores the regulatory role of pH in this vital cellular process. KDELR2 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived KDELR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

-20°C

41116100

Mouse