KDM2B Antibody

Cusabio

KDM2B Antibody

20

ImmunoFluorescence, ELISA

Research Use Only

Polyclonal

Unconjugated

KDM2B

lysine demethylase 2B

CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2, lysine-specific demethylase 2B, CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein, [Histone-H3]-lysine-36 demethylase 1B, jmjC domain-containing histone demethylation protein 1B, jumonji C domain-containing histone demethylase 1B, lysine (K)-specific demethylase 2B, protein-containing CXXC domain 2

Rabbit

IgG

Lysine-specific demethylase 2B

Histone demethylase that demethylates Lys-4 and Lys-36 of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 Lys-4 and dimethylated H3 Lys-36 residue while it has weak or no activity for mono- and tri-methylated H3 Lys-36. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Human

-20°C or -80°C

41116161