The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA052445(KDM3B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)

KDM3B Antibody

CSB-PA052445

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse

TargetKDM3B

Overview

Supplier
Cusabio
Product Name
KDM3B Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID51780
Target name
KDM3B
Target description
lysine demethylase 3B
Target synonyms
[histone H3]-dimethyl-L-lysine(9) demethylase 3B; 5qNCA; C5orf7; DIJOS; jmjC domain-containing histone demethylation protein 2B; JMJD1B; jumonji domain containing 1B; jumonji domain-containing protein 1B; lysine (K)-specific demethylase 3B; lysine-specific demethylase 3B; NET22; nuclear protein 5qNCA
Host
Rabbit
Isotype
IgG
Protein IDQ7LBC6
Protein Name
Lysine-specific demethylase 3B
Scientific Description
JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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