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ProductsBack/KDM4-IN-2 [2369607-62-3]
CgoaEGY7M9KEff8JAAAAAARGRSE666.png
CgoaEGY7M9KEff8JAAAAAARGRSE666.png
CgoaEGY7M9KEff8JAAAAAARGRSE666.png

KDM4-IN-2 [2369607-62-3]

Research Use Only
T11749
TargetMol Chemicals
CAS Number2369607-62-3
DownloadMSDS
Product group Chemicals
Molecular Weight426.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    KDM4-IN-2 [2369607-62-3]
  • Delivery Days Customer
    86
  • CAS Number
    2369607-62-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    KDM4-IN-2
  • Molecular Formula
    C25H26N6O
  • Molecular Weight
    426.51
  • Scientific Description
    KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC3(CCc4ccccc34)CC2)cn1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Le Bihan YV, et al. C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur J Med Chem. 2019 Sep 1;177:316-337.
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