KDM4-IN-4 [2230475-63-3]

MedChem Express

KDM4-IN-4 [2230475-63-3]

10

2230475-63-3

Research Use Only

C16H23NO

245.36

KDM4-IN-4 (compound 47) is a potent histone lysine demethylase 4 (KDM4) inhibitor with a modest affinity binding to ~80 microM for KDM4A-Tudor domain. KDM4-IN-4 can inhibit H3K4Me3 binding to the Tudor domain in cells with an EC50 value of 105 microM. KDM4-IN-4 can be used for researching anticancer[1].

O[C@@H]1[C@@]2(C3=CC=CC=C3)C[C@H](CC2)[C@@H]1CN(C)C

12131703