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Keap1 Antibody

Research Use Only
CSB-PA012147LA01MO
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetKeap1
Price on request
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    Keap1 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID50868
  • Target name
    Keap1
  • Target description
    kelch-like ECH-associated protein 1
  • Target synonyms
    cytosolic inhibitor of Nrf2; IN; INRF2; kelch-like ECH-associated protein 1; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Z2X8
  • Protein Name
    Kelch-like ECH-associated protein 1
  • Scientific Description
    Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203