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Keap1-Nrf2-IN-9 [2769963-24-6]
T74600
Overview
- SupplierTargetMol Chemicals
- Product NameKeap1-Nrf2-IN-9 [2769963-24-6]
- Delivery Days Customer999
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameKeap1-Nrf2-IN-9
- Molecular FormulaC31H30N2O11S2
- Molecular Weight670.71
- Scientific DescriptionKeap1-Nrf2-IN-9 (compound 11) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with an IC50 value of 0.575 microM, enhancing the expression of Nrf2 target genes such as heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits, while not being cytotoxic to ARPE19 cells [1].
- Shelf life instruction3 years
- SMILESCOc1ccc(cc1)S(=O)(=O)N(CC(O)=O)c1ccc(N(CC(O)=O)S(=O)(=O)c2ccc(OC)cc2)c(OCc2ccccc2)c1
- Storage Instruction-20°C
- UNSPSC51202000