Kenpaullone [142273-20-9]
HY-12302
CAS Number142273-20-9
Product group Chemicals
Estimated Purity98.20
Molecular Weight327.18
Overview
- SupplierMedChem Express
- Product NameKenpaullone [142273-20-9]
- Delivery Days Customer10
- CAS Number142273-20-9
- Category SupplierCHEMICAL,general_chemicals_reagents
- CertificationResearch Use Only
- Estimated Purity98.20
- Molecular FormulaC16H11BrN2O
- Molecular Weight327.18
- Scientific DescriptionKenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3beta, with IC50s of 0.4 microM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 microM, 7.5 microM, 0.85 microM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro.
- SMILESO=C1NC2=CC=CC=C2C(NC3=C4C=C(Br)C=C3)=C4C1
- Storage Instruction-20°C, 3 years; 4°C, 2 years (Powder)
- UNSPSC12352200
MSDS
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