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Ketopioglitazone

HY-119311
MedChem Express
CAS Number146062-45-5
Product group Chemicals
Molecular Weight370.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ketopioglitazone [146062-45-5]
  • Delivery Days Customer
    5
  • CAS Number
    146062-45-5
  • Certification
    Research Use Only
  • Molecular Formula
    C19H18N2O4S
  • Molecular Weight
    370.42
  • Scientific Description
    Pioglitazone ketone is an active metabolite of the PPARgamma agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.
  • SMILES
    O=C(SC1CC2=CC=C(C=C2)OCCC3=NC=C(C=C3)C(C)=O)NC1=O
  • UNSPSC
    12352200

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