Ketopioglitazone
HY-119311
Overview
- SupplierMedChem Express
- Product NameKetopioglitazone [146062-45-5]
- Delivery Days Customer5
- CAS Number146062-45-5
- CertificationResearch Use Only
- Molecular FormulaC19H18N2O4S
- Molecular Weight370.42
- Scientific DescriptionPioglitazone ketone is an active metabolite of the PPARgamma agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.
- SMILESO=C(SC1CC2=CC=C(C=C2)OCCC3=NC=C(C=C3)C(C)=O)NC1=O
- UNSPSC12352200