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ProductsBack/Ki16425 [355025-24-0]

Ki16425 [355025-24-0]

Research Use Only
HY-13285
MedChem Express
CAS Number355025-24-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.11
Molecular Weight474.96
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ki16425 [355025-24-0]
  • Delivery Days Customer
    10
  • CAS Number
    355025-24-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.11
  • Molecular Formula
    C23H23ClN2O5S
  • Molecular Weight
    474.96
  • Scientific Description
    Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 microM and 0.93 microM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK[1][2]. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells[3].
  • SMILES
    ClC1=C(C=CC=C1)C(C)OC(NC2=C(ON=C2C)C3=CC=C(C=C3)CSCCC(O)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200