Ki16425
HY-13285
Overview
- SupplierMedChem Express
- Product NameKi16425 [355025-24-0]
- Delivery Days Customer10
- CAS Number355025-24-0
- CertificationResearch Use Only
- Estimated Purity98.88
- Molecular FormulaC23H23ClN2O5S
- Molecular Weight474.96
- Scientific DescriptionKi16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 microM and 0.93 microM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK[1][2]. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells[3].
- SMILESClC1=C(C=CC=C1)C(C)OC(NC2=C(ON=C2C)C3=CC=C(C=C3)CSCCC(O)=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200