Ki20227
HY-10408
Overview
- SupplierMedChem Express
- Product NameKi20227 [623142-96-1]
- Delivery Days Customer5
- CAS Number623142-96-1
- CertificationResearch Use Only
- Estimated Purity99.51
- Molecular FormulaC24H24N4O5S
- Molecular Weight480.54
- Scientific DescriptionKi20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC 50 s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRbeta (platelet-derived growth factor receptor beta). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction [1] .
- SMILESO=C(NC1=CC=C(C=C1OC)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC(C)C4=NC=CS4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200