KIF18A-IN-4 [1197522-21-6]

MedChem Express

KIF18A-IN-4 [1197522-21-6]

10

1197522-21-6

Research Use Only

C22H27N3O3S

413.53

KIF18A-IN-4 is a moderately potent ATP and microtubule (MT) noncompetitive KIF18A inhibitor (IC50=6.16 microM). KIF18A-IN-4 has selectivity against a large panel of mitotic kinesins and kinases, and does not show any direct effects on tubulin assembly. KIF18A-IN-4 exhibits anti-tumor activity[1].

O=S(C1=CC=CC(NC(C2=C(N3CCCCC3)N=CC=C2)=O)=C1)(C4CCCC4)=O

12131703