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KIF22 antibody [N3C2], Internal

GTX112357
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetKIF22
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Overview

  • Supplier
    GeneTex
  • Product Name
    KIF22 antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:29382784)
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3835
  • Target name
    KIF22
  • Target description
    kinesin family member 22
  • Target synonyms
    A-328A3.2; KID; kinesin-like DNA-binding protein pseudogene; kinesin-like protein 4; kinesin-like protein KIF22; KNSL4; OBP; OBP-1; OBP-2; origin of plasmid DNA replication-binding protein; oriP binding protein; SEMDJL2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14807
  • Protein Name
    Kinesin-like protein KIF22
  • Scientific Description
    The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. [provided by RefSeq]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation.
    Read more
  • KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation. Pike R et al., 2018 Jan 30, Sci Signal
    Read more