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KIR3DL3/IL-2 Luciferase Reporter Jurkat Cell Line

KIR3DL3/IL-2 Luciferase Reporter Jurkat Cell Line

Research Use Only
78322
BPS Bioscience
Product group (Cell) Culture
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    KIR3DL3/IL-2 Luciferase Reporter Jurkat Cell Line
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    Recombinant Jurkat cell line expressing firefly luciferase under the control of an IL-2-responsive promoter, and with constitutive expression of human KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains and Long Cytoplasmic Tail 3; GenBank accession #BC143802.1 corresponding to KIR3DL3*00402 allele). HHLA2 (B7-H7) mediates an immune-stimulatory signal via TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H) in naIve T cells while it delivers an immune-inhibitory signal through KIR3DL3 in activated T cells and Natural Killer (NK) cells.
  • Storage Instruction
    Liquid Nitrogen
  • UNSPSC
    12352207

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