KLC1 Polyclonal Antibody
RD83361A
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKLC1
Overview
- SupplierReddot Biotech
- Product NameKLC1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3831
- Target nameKLC1
- Target descriptionkinesin light chain 1
- Target synonymskinesin 2 60/70kDa; kinesin light chain 1; KLC; KNS2; KNS2A; medulloblastoma antigen MU-MB-2.50
- HostRabbit
- IsotypeIgG
- Scientific DescriptionConventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203