KLF1 Polyclonal Antibody

Reddot Biotech

KLF1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.96 mg/ml

Unconjugated

KLF1

KLF transcription factor 1

CDAN4A, CDAN4B, EKLF, EKLF/KLF1, Krueppel-like factor 1, Kruppel like factor 1, erythroid Kruppel-like factor, erythroid krueppel-like transcription factor, erythroid-specific transcription factor EKLF

Rabbit

IgG

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Human

-20°C

12352203