KLHDC2-IN-1

MedChem Express

KLHDC2-IN-1

999

Research Use Only

C22H19ClF3NO3

437.84

KLHDC2-IN-1 (Compound 6) is a ligand targeting the ubiquitin E3 ligase KLHDC2 (Kd: 160 nM). KLHDC2-IN-1 enables the synthesis of a PROTAC that can effectively degrade BRD4 in cells[1].

OC(C1=C2C(C(C3CCC4C3)C4C(C5=CC(OC(F)(F)F)=CC=C5)N2)=CC(Cl)=C1)=O

12352200