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Western blot All lanes: KLHL22 antibody at 8microg/ml Lane 1: Jurkat whole cell lysate Lane 2: NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 72, 56 kDa Observed band size: 72 kDa
Western blot All lanes: KLHL22 antibody at 8microg/ml Lane 1: Jurkat whole cell lysate Lane 2: NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 72, 56 kDa Observed band size: 72 kDa
Western blot All lanes: KLHL22 antibody at 8microg/ml Lane 1: Jurkat whole cell lysate Lane 2: NIH/3T3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 72, 56 kDa Observed band size: 72 kDa

KLHL22 Antibody

CSB-PA684469LA01HU
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetKLHL22
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Overview

  • Supplier
    Cusabio
  • Product Name
    KLHL22 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID84861
  • Target name
    KLHL22
  • Target description
    kelch like family member 22
  • Target synonyms
    KELCHL; kelch-like 22; kelch-like protein 22
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ53GT1
  • Protein Name
    Kelch-like protein 22
  • Scientific Description
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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