KLK7 Polyclonal Antibody

Elabscience

KLK7 Polyclonal Antibody

12

Western Blot

ELISA WB IHC

Research Use Only

Polyclonal

0.1 mg/ml

Unconjugated

KLK7

kallikrein related peptidase 7

PRSS6, SCCE, hK7, kallikrein-7, kallikrein 7 (chymotryptic, stratum corneum), serine protease 6, signal protein, stratum corneum chymotryptic enzyme

Rabbit

IgG

Kallikrein-7

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

-20°C

41116161