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Klotho beta, Human (HEK293, His)

HY-P77972
MedChem Express
Protein IDQ86Z14
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Klotho beta, Human (HEK293, His)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    97.0
  • Gene ID152831
  • Target name
    KLB
  • Target description
    klotho beta
  • Target synonyms
    BKL, beta-klotho, b-Klotho, betaKlotho, klotho beta like, klotho beta-like protein
  • Protein IDQ86Z14
  • Protein Name
    Beta-klotho
  • Scientific Description
    Klotho beta protein plays a critical role in the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), a key enzyme controlling bile acid synthesis. Although its glycosidase activity may be inactive, Klotho beta enhances the binding ability of FGFR1 and FGFR4 to FGF21, promoting their interaction. Klotho beta Protein, Human (HEK293, His) is the recombinant human-derived Klotho beta protein, expressed by HEK293 , with C-His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100