KMT5B Antibody

Cusabio

KMT5B Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

KMT5B

lysine methyltransferase 5B

CGI-85, CGI85, MRD51, SUV420H1, histone-lysine N-methyltransferase KMT5B, [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B, [histone H4]-lysine20 N-methyltransferase KMT5B, histone-lysine N-methyltransferase SUV420H1, lysine (K)-specific methyltransferase 5B, lysine N-methyltransferase 5B, lysine-specific methyltransferase 5B, su(var)4-20 homolog 1, suppressor of variegation 4-20 homolog 1

Rabbit

IgG

Histone-lysine N-methyltransferase KMT5B

Histone methyltransferase that specifically trimethylates Lys-20 of histone H4. H4 Lys-20 trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.

Human

-20°C or -80°C

41116161