Ko 143

MedChem Express

Ko 143 [461054-93-3]

10

461054-93-3

Research Use Only

99.97

C26H35N3O5

469.57

Ko 143 is a potent and selective ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor. Ko 143 displays >200-fold selectivity over P-gp and MRP-1 transporters [1] [2] .

O=C1N2[C@]([H])(C3=C(C[C@]2(C(N[C@H]1CCC(OC(C)(C)C)=O)=O)[H])C4=CC=C(OC)C=C4N3)CC(C)C

-20°C,2°C to 8°C

12352200