Kobe0065 [436133-68-5]

MedChem Express

Kobe0065 [436133-68-5]

10

436133-68-5

Research Use Only

98.01

C15H11ClF3N5O4S

449.79

Kobe0065 is a novel and effective inhibitor of Ras-Raf interaction, competitively inhibiting the binding of H-Ras GTP to c-Raf-1 RBD with a Ki value of 46+/-13 microM.

FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(C)C(Cl)=C2)=S)C([N+]([O-])=O)=C1)(F)F

-20°C,2°C to 8°C

12352200