Kobe2602

MedChem Express

Kobe2602 [454453-49-7]

10

454453-49-7

Research Use Only

98.15

C14H9F4N5O4S

419.31

Kobe2602 is a Ras-Raf interaction inhibitor. Kobe2602 inhibits the binding of H-Ras GTP to c-Raf-1 RBD with a K i of 149 microM. Kobe2602 has antitumor activity [1] .

FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(F)C=C2)=S)C([N+]([O-])=O)=C1)(F)F

-20°C

12352200