Kojic acid

MedChem Express

Kojic acid [501-30-4]

10

501-30-4

Research Use Only

99.99

C6H6O4

142.11

Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC 50 of 182.7 microM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-kappaB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity [1] [2] [3] [4] [5] [6] [7] [8] .

O=C1C=C(CO)OC=C1O

-20°C,2°C to 8°C

12352200