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KP-457

HY-110397
MedChem Express
CAS Number1365803-52-6
Product group Chemicals
Estimated Purity99.18
Molecular Weight480.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KP-457 [1365803-52-6]
  • Delivery Days Customer
    5
  • CAS Number
    1365803-52-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.18
  • Molecular Formula
    C21H24N2O7S2
  • Molecular Weight
    480.55
  • Scientific Description
    KP-457 is a selective a disintegrin and metalloproteinase 17 ( ADAM17 ) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC 50 s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.
  • SMILES
    CS(=O)(NCC1=CC=C(C(N(C=O)O)CS(=O)(C2=CC=C(OCC#CC)C=C2)=O)C=C1)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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