KPC-2-IN-1 [2232877-85-7]

MedChem Express

KPC-2-IN-1 [2232877-85-7]

10

2232877-85-7

Research Use Only

C13H12BN3O2S

285.13

KPC-2-IN-1, boronic acid derivative, is a potent KPC-2 inhibitor with Ki of 0.032 microM. KPC-2-IN-1 enhances the activity of cefotaxime in KPC-2 expressing E. coli. KPC-2-IN-1 exhibits well tolerated in human HEK-293 cells, which can be used for the study of E. coli resistance to beta-lactam antibiotics[1][2].

OB(C1=CC=CC(CN2N=NC(C3=CSC=C3)=C2)=C1)O

12131703