KR-31378 [335381-68-5]

MedChem Express

KR-31378 [335381-68-5]

9

335381-68-5

Research Use Only

C22H27N5O4

425.48

KR-31378 is a neuroprotectant with dose-dependent pharmacokinetic properties and relevant activity in rats. After intravenous and oral administration of KR-31378 in rats, its pharmacokinetic parameters showed dose-dependent changes, such as decreased clearance with increasing doses, good oral absorption, and comparable AUCs for intravenous and oral administration at different doses.

N#CN/C(NCC1=CC=CC=C1)=N\[C@@H]2C3=CC(N)=CC=C3O[C@@](C)([C@H]2O)C(OC)OC

12352200