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KRAS (G12C) Isoform A Coupled Nucleotide Exchange (TR-FRET) Assay Kit

Name: KRAS (G12C) Isoform A Coupled Nucleotide Exchange (TR-FRET) Assay Kit
SKU: 82709_B75
Availability: BackOrder

82709

Product group Assays

Overview

Supplier
BPS Bioscience
Product Name
KRAS (G12C) Isoform A Coupled Nucleotide Exchange (TR-FRET) Assay Kit
Delivery Days Customer
23
Applications
Neutralisation/Blocking
Certification
Research Use Only
Scientific Description
The KRAS (G12C) Isoform A Coupled Nucleotide Exchange TR-FRET Assay Kit is a TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) assay kit designed for screening and profiling of KRAS (Kirsten rat sarcoma) (G12C) antagonists/inhibitors. It monitors the binding of an effector protein such as the Ras binding domain of Raf1, (RBD-cRAF), to KRAS(G12C). The KRAS(G12C) Isoform A Coupled Nucleotide Exchange TR-FRET Assay Kit comes in a convenient 384-well format, with enough purified recombinant GDP-loaded KRAS(G12C) Isoform A, GTP, exchange factor SOS1 (son of sevenless homolog 1) (amino acids 564-1049), effector protein RBD-cRAF (amino acids 50-140), assay buffer and additives for 400 reactions.
UNSPSC
41116133