Bio-Connect

KRAS inhibitor-14 [2230873-78-4]

HY-146544
MedChem Express
CAS Number2230873-78-4
Product group Chemicals
Molecular Weight486.77
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KRAS inhibitor-14 [2230873-78-4]
  • Delivery Days Customer
    10
  • CAS Number
    2230873-78-4
  • Certification
    Research Use Only
  • Molecular Formula
    C20H15Cl3FN3O2S
  • Molecular Weight
    486.77
  • Scientific Description
    KRAS inhibitor-14 (compound 3-22) is a potent KRAS G12C inhibitor with an IC50 of 0.249 microM. KRAS inhibitor-14 shows p-ERK inhibition activities with IC50s of 1.12, >33.3 microM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-14 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
  • SMILES
    C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(O)=CC(Cl)=C4Cl)=C(C3=NS2)F)Cl)=O
  • UNSPSC
    12131703