KRAS inhibitor-14 [2230873-78-4]
HY-146544
Overview
- SupplierMedChem Express
- Product NameKRAS inhibitor-14 [2230873-78-4]
- Delivery Days Customer10
- CAS Number2230873-78-4
- CertificationResearch Use Only
- Molecular FormulaC20H15Cl3FN3O2S
- Molecular Weight486.77
- Scientific DescriptionKRAS inhibitor-14 (compound 3-22) is a potent KRAS G12C inhibitor with an IC50 of 0.249 microM. KRAS inhibitor-14 shows p-ERK inhibition activities with IC50s of 1.12, >33.3 microM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-14 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
- SMILESC=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(O)=CC(Cl)=C4Cl)=C(C3=NS2)F)Cl)=O
- UNSPSC12131703