Bio-Connect

KRAS inhibitor-15 [2230873-75-1]

HY-146545
MedChem Express
CAS Number2230873-75-1
Product group Chemicals
Molecular Weight451.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KRAS inhibitor-15 [2230873-75-1]
  • Delivery Days Customer
    10
  • CAS Number
    2230873-75-1
  • Certification
    Research Use Only
  • Molecular Formula
    C20H17Cl2FN4OS
  • Molecular Weight
    451.34
  • Scientific Description
    KRAS inhibitor-15 (compound 3-19) is a potent KRAS G12C inhibitor with an IC50 of 0.954 microM. KRAS inhibitor-15 shows p-ERK inhibition activities with IC50s of 2.03, >33.3 microM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-15 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
  • SMILES
    C=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(N)=CC=C4Cl)=C(C3=NS2)F)Cl)=O
  • UNSPSC
    12131703