KRAS inhibitor-15 [2230873-75-1]
HY-146545
CAS Number2230873-75-1
Product group Chemicals
Molecular Weight451.34
Overview
- SupplierMedChem Express
- Product NameKRAS inhibitor-15 [2230873-75-1]
- Delivery Days Customer10
- CAS Number2230873-75-1
- CertificationResearch Use Only
- Molecular FormulaC20H17Cl2FN4OS
- Molecular Weight451.34
- Scientific DescriptionKRAS inhibitor-15 (compound 3-19) is a potent KRAS G12C inhibitor with an IC50 of 0.954 microM. KRAS inhibitor-15 shows p-ERK inhibition activities with IC50s of 2.03, >33.3 microM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-15 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
- SMILESC=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(N)=CC=C4Cl)=C(C3=NS2)F)Cl)=O
- UNSPSC12131703