KRAS inhibitor-16 [2230873-67-1]
HY-146546
CAS Number2230873-67-1
Product group Chemicals
Molecular Weight452.33
Overview
- SupplierMedChem Express
- Product NameKRAS inhibitor-16 [2230873-67-1]
- Delivery Days Customer10
- CAS Number2230873-67-1
- CertificationResearch Use Only
- Molecular FormulaC20H16Cl2FN3O2S
- Molecular Weight452.33
- Scientific DescriptionKRAS inhibitor-16 (compound 3-11) is a potent KRAS G12C inhibitor with an IC50 of 0.457 microM. KRAS inhibitor-16 shows p-ERK inhibition activities with IC50s of 3.06, 11.1 microM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-16 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
- SMILESC=CC(N1CCN(CC1)C2=C3C=C(C(C4=CC(O)=CC=C4Cl)=C(C3=NS2)F)Cl)=O
- UNSPSC12131703