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KRN 633

M3269
AbMole BioScience
CAS Number286370-15-8
DownloadDatasheet
Product group Chemicals
Estimated Purity>98%
Molecular Weight416.86
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    KRN 633
  • Delivery Days Customer
    9
  • CAS Number
    286370-15-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C20H21ClN4O4
  • Molecular Weight
    416.86
  • Scientific Description
    KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-alfa/bèta and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
  • SMILES
    CCCNC(=O)NC1=CC=C(OC2=NC=NC3=CC(=C(OC)C=C23)OC)C=C1Cl
  • UNSPSC
    12352200

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