KRP-199 [221164-28-9]
HY-117176
CAS Number221164-28-9
Product group Chemicals
Molecular Weight517.37
Overview
- SupplierMedChem Express
- Product NameKRP-199 [221164-28-9]
- Delivery Days Customer5
- CAS Number221164-28-9
- CertificationResearch Use Only
- Molecular FormulaC22H14F3N5O7
- Molecular Weight517.37
- Scientific DescriptionKRP-199 (compound 14h) is an alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid receptor (AMPA-R) antagonist (Ki=16 nM) with high potency and selectivity for AMPA-R in vitro and good neuroprotective effects in vivo. KRP-199 can be used in the study of neurodegenerative diseases[1].
- SMILESO=C(C1=NC2=C(C=C(C(F)(F)F)C(N3C=C(COC(NC4=CC=C(C(O)=O)C=C4)=O)N=C3)=C2)NC1=O)O
- UNSPSC12352200