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Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CK-6A/B/C Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CK-6A/B/C Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CK-6A/B/C Polyclonal Antibody at dilution 1:50

KRT6A/KRT6B/KRT6C Polyclonal Antibody

Research Use Only
E-AB-15555
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    KRT6A/KRT6B/KRT6C Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.4mg/ml
  • Scientific Description
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
  • UNSPSC
    12352203