KS15 [1033781-20-2]

TargetMol Chemicals

KS15

14

1033781-20-2

Chemical

Research Use Only

KS15

C20H22BrNO4

420.303

KS15 is a chemical compound that acts as an inhibitor on the interactions between cryptochromes, specifically CRY1 and CRY2, and the CLOCK: BMAL1 heterodimer. This compound, with an EC50 value of 4.9 microM, hinders the feedback actions of CRYs on E-box-dependent transcription. The CLOCK: BMAL1 heterodimer is a vital transcriptional regulator for the mammalian circadian clock. In addition, KS15 exhibits significant anti-proliferative activity.

3 years

CCO[C@H](Cc1cccc(c1)C(\C)=N\OCc1ccc(Br)cc1)C(O)=O

-20°C

12352200