KS176 [1253452-78-6]

MedChem Express

KS176 [1253452-78-6]

5

1253452-78-6

Research Use Only

99.09

C22H19N3O5

405.40

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 microM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1. IC50 value: 0.59( in Pheo A assay), 1.39 microM (in Hoechst 33342 assay). Target: BCRP The more detailed information please refer to Compound 9 in the reference.

O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3

-20°C,2°C to 8°C

12352200