KT5823

MedChem Express

KT5823 [126643-37-6]

9

126643-37-6

Research Use Only

99.90

C29H25N3O5

495.53

KT5823, a selective the cGMP-dependent protein kinase ( PKG ) inhibitor with an K i value of 0.23 microM, it also inhibits PKA and PKC with K i values of 10 microM and 4 microM, respectively. KT5823 is a Staurosporine -related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na + /I - symporter) NIS expression, and iodide uptake in thyroid cells. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels of apoptotic DNA fragmentation [1] [2] [3] [4] [5] .

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-20°C

12352200