KTSAVLQ-Rhodamine110-gamma-Glu

South Bay Bio

KTSAVLQ-Rhodamine110-gamma-Glu

10

Research Use Only

>99%

Chemical. Molecular Weight: 1187.3. KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving between the glutamine and the Rhodamine110 fluorophore. Prior hydrolysis, the Rhodamine110 moiety is quenched resulting in a very low background. This substrate is ideal for activity determination of 3CLpro and suitable for HTS or pilot screens in search for potential inhibitors due to its red-shifted fluorescence compared to AMC or Dabcyl/Edans substrates. This results in less interference with potential inhibitors in screeing campaigns. Ex/Em=485nm/535nm (recommended). - KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving between the glutamine and the Rhodamine110 fluorophore. Prior hydrolysis, the Rhodamine110 moiety is quenched resulting in a very low background. This substrate is ideal for activity determination of 3CLpro and suitable for HTS or pilot screens in search for potential inhibitors due to its red-shifted fluorescence compared to AMC or Dabcyl/Edans substrates. This results in less interference with potential inhibitors in screeing campaigns. Ex/Em=485nm/535nm (recommended).

-20°C,2°C to 8°C

12352202